Since 90 time, world dairy production and steady development. The developed country milk production accounted for 50% of the world, China's dairy industry is in after ninety years of rapid development, in 2004, the per capita dairy has reached 14kg. Dairy enterprises have increased, competition is intense. While dairy fake is the dairy industry encountered a serious problem: adulteration phenomenon. This article lists in milk mixed with water, starch, rice, soybean milk and sugar and several common adulterate dopant, and put forward effective detection method; reviews the emerging high performance liquid chromatography, biosensor and modern detection methods in milk adulteration adulteration detection application.